Ulcerative colitis is limited to which tissue layer?

Ulcerative colitis is limited to which tissue layer?

• A. Colon lining
• B. Entire bowel wall
• C. Submucosa only
• D. Mucosa of the stomach

Answer: (A)

Ulcerative colitis inflammation is confined to the mucosal lining of the colon (the inner lining). This disease typically affects the colon’s mucosa, sometimes extending into the submucosa, but it does not involve the full thickness of the bowel wall. That’s why the colon lining best fits the pattern of UC. In contrast, conditions like Crohn’s can involve deeper layers of the intestinal wall (transmural) and can occur anywhere along the GI tract, which helps distinguish them. The stomach lining isn’t involved in ulcerative colitis, since the disease targets the colon.

Ulcerative colitis inflammation is confined to the mucosal lining of the colon (the inner lining). This disease typically affects the colon’s mucosa, sometimes extending into the submucosa, but it does not involve the full thickness of the bowel wall. That’s why the colon lining best fits the pattern of UC. In contrast, conditions like Crohn’s can involve deeper layers of the intestinal wall (transmural) and can occur anywhere along the GI tract, which helps distinguish them. The stomach lining isn’t involved in ulcerative colitis, since the disease targets the colon.